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Braintree/TCS Taurolidine-Citrate Solution/case of 10 - 7 ml vials/TCS CS
TCS,acatheterlocksolution,combinestwoactiveingredientsvitaltotheeffectivemanagementofvascularaccesscatheters;TaurolidineandCitrate.WhenTCSisinstilledindevicelumens,theirinternalflowpassagesareresistanttoclotformationandhostiletobacterialandfungalgrowth.TCSisnon-toxicandtherearenoknownsystemiceffects.Taurolidine,ananti-microbialagent,promotescatheterpatencybypreventingBiofilmformationwhileCitrate,actsastheanticoagulant.
thetaurolidinecomponentoffersbroadspectrumantimicrobialactivityagainstaerobicandanaerobicgram-positiveandgram-negativebacteria,yeastandfungiinteractswiththecomponentsofmicrobialcellwalls,resultinginirreparableinjurypreventsbiofilmdevelopmentandconsequentlybacterialandfungalcolonization,decreasingtheriskofinfectiondoesnotinducethedevelopmentofresistantmicrobes.
thecitratecomponentformsacomplexwithcalcium,disruptingthenormalcoagulationcascade,precipitatingitintoanunusableforminhibitingbloodcoagulationwithnosystemiceffect.
TCSiseffectiveinthepreventionofcatheterassociatedinfectionsandocclusionsinalllaboratoryspeciesfromrodentstonon-humanprimates.TCShasafavorablesafetyprofile.Itisnon-toxicandhasnoknowntopicalorsystemiceffect.NodevelopmentofresistancetoTCShasbeenreported.
